Metaxalone

MedChem Express

Metaxalone [1665-48-1]

10

1665-48-1

Research Use Only

99.77

C12H15NO3

221.256

Metaxalone (AHR438; NSC170959) is an FDA-approved muscle relaxant. Metaxalone acts mainly on the central nervous system and achieves muscle relaxation by inhibiting polysynaptic reflex arcs. In addition, Metaxalone is an inhibitor of MAO-A, which has anti-inflammatory and antioxidant effects. Metaxalone inhibits IL-1beta-induced inflammatory phenotype, modulates NF-kappaB and other related signaling pathways, and decreases MAO-A expression and activity in IL-1beta-treated microglia [1] [2] .

O=C1OC(COC2=CC(C)=CC(C)=C2)CN1

-20°C,2°C to 8°C

12352200