Methoxy-X04 [863918-78-9]

MedChem Express

Methoxy-X04 [863918-78-9]

10

863918-78-9

Research Use Only

98.46

C23H20O3

344.40

Methoxy-X04 is a fluorescent dye that crosses the blood-brain barrier and selectively binds to beta-pleated sheets found in dense core amyloid Abeta plaques. Methoxy-X04 retains in vitro binding affinity for amyloid b (Ab) fibrils (Ki= 26.8 nM). Methoxy-X04 is fluorescent and stains plaques, tangles, and cerebrovascular amyloid in postmortem sections of AD brain with good specificity[1][2].

COC1=CC(/C=C/C2=CC=C(O)C=C2)=CC=C1/C=C/C3=CC=C(O)C=C3

2°C to 8°C

41116134