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Methoxyamine (hydrochloride)

HY-Y0958
MedChem Express
CAS Number593-56-6
DownloadMSDS
Product group Chemicals
Estimated Purity98.0
Molecular Weight83.52
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Methoxyamine (hydrochloride) [593-56-6]
  • Delivery Days Customer
    10
  • CAS Number
    593-56-6
  • Certification
    Research Use Only
  • Estimated Purity
    98.0
  • Molecular Formula
    CH6ClNO
  • Molecular Weight
    83.52
  • Scientific Description
    Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor. Methoxyamine hydrochloride binds to 3 hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity. Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites. Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents[1][2].
  • SMILES
    NOC.[H]Cl
  • Storage Instruction
    RT
  • UNSPSC
    12352200

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