Methyltetrazine-Ph-PEG4-azide [1802908-04-8]
HY-130508
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NameMethyltetrazine-Ph-PEG4-azide [1802908-04-8]
- Delivery Days Customer10
- CAS Number1802908-04-8
- CertificationResearch Use Only
- Molecular FormulaC17H23N7O4
- Molecular Weight389.41
- Scientific DescriptionMethyltetrazine-Ph-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Methyltetrazine-Ph-PEG4-azide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
- SMILESCC1=NN=C(C2=CC=C(OCCOCCOCCOCCN=[N+]=[N-])C=C2)N=N1
- UNSPSC41115800