METTL7A antibody

GeneTex

METTL7A antibody

9

At least two isoforms of MettL7A are known to exist. This antibody is predicted to not cross-react with MettL7B.

WB: 2 microg/mL. ICC/IF: 2 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

METTL7A

methyltransferase like 7A

AAMB; AAM-B; methyltransferase-like protein 7A; protein AAM-B

Rabbit

IgG

Methyltransferase-like protein 7A

MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis. At least two isoforms of MettL7A are known to exisit. This antibody is predicted to not cross-react with MettL7B.

Human, Mouse

2°C to 8°C

12352203