Mexiletine-d3

MedChem Express

Mexiletine-d3

5

Research Use Only

C11H14D3NO

182.28

Mexiletine-d3 (KOE-1173-d3) is deuterium labeled Mexiletine. Mexiletine is an orally effective antiarrhythmic agent which has also been found to be effective for myotonia and neuropathic pain. Mexiletine exerts its efficacy through blocking sodium channels (IC50 : 75+/-8 microM for tonic block, 23.6+/-2.8 microM for use-dependent block), therefore can be used for cardiovascular and neurological research[1][2][3][4][5].

CC(N)COC1=C(C)C([2H])=C([2H])C([2H])=C1C

12352200