The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA797342(MGEA5 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200)

MGEA5 Antibody

Name: MGEA5 Antibody
SKU: CSB-PA797342_C90
Availability: BackOrder

CSB-PA797342

ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman, Mouse, Rat

TargetOGA

Overview

Supplier
Cusabio
Product Name
MGEA5 Antibody
Delivery Days Customer
20
Applications
Western Blot, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID10724
Target name
OGA
Target description
O-GlcNAcase
Target synonyms
MEA5, MGEA5, NCOAT, protein O-GlcNAcase, N-acetyl-beta-D-glucosaminidase, N-acetyl-beta-glucosaminidase, beta-N-acetylglucosaminidase, beta-N-acetylhexosaminidase, beta-hexosaminidase, bifunctional protein NCOAT, hyaluronidase in meningioma, meningioma expressed antigen 5 (hyaluronidase), meningioma-expressed antigen 5, nuclear cytoplasmic O-GlcNAcase and acetyltransferase
Host
Rabbit
Isotype
IgG
Protein IDO60502
Protein Name
Protein O-GlcNAcase
Scientific Description
The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT, which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications. Cleaves GlcNAc but not GalNAc from glycopeptides. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc. Possesses hyaluronidase activity. Acetylates Lys-8 of histone H4 and Lys-14 of histone H3. Shows highest expression in the brain, placenta and pancreas.
Reactivity
Human, Mouse, Rat
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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MGEA5 Antibody

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