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mGluR7 antibody

Research Use Only
GTX71717
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human
TargetGRM7
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Overview

  • Supplier
    GeneTex
  • Product Name
    mGluR7 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 6 - 16 microg/ml. IHC-P: 6 - 16 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID2917
  • Target name
    GRM7
  • Target description
    glutamate metabotropic receptor 7
  • Target synonyms
    GLUR7; glutamate receptor, metabotropic 7; GPRC1G; metabotropic glutamate receptor 7; MGLU7; MGLUR7; NEDSHBA; PPP1R87; protein phosphatase 1, regulatory subunit 87
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ14831
  • Protein Name
    Metabotropic glutamate receptor 7
  • Scientific Description
    L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
  • Reactivity
    Bovine, Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203