mHTT-IN-1 [2839311-21-4]
HY-150245
CAS Number2839311-21-4
Product group Chemicals
Molecular Weight381.45
Overview
- SupplierMedChem Express
- Product NamemHTT-IN-1 [2839311-21-4]
- Delivery Days Customer10
- CAS Number2839311-21-4
- CertificationResearch Use Only
- Molecular FormulaC18H19N7OS
- Molecular Weight381.45
- Scientific DescriptionmHTT-IN-1 (Example 1) is a potent mutant huntingtin (mHTT) inhibitor. mHTT is toxic and a major cause of the inherited autosomal dominant neurodegenerative disorder, Huntingtons disease (HD). mHTT-IN-1 conducts the reduction of mHTT with an EC50 value of 46 nM[1].
- SMILESO=C1C=C(C2=NN3C=C(C)N=C3C(C)=C2)N=C4SC(N5CCNCC5)=CN14
- UNSPSC12131703