MICAL2 Antibody, Biotin conjugated

Cusabio

MICAL2 Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

MICAL2

microtubule associated monooxygenase, calponin and LIM domain containing 2

Ebitein1, MICAL-2, MICAL2PV1, MICAL2PV2, MICALCL, mical-cL, [F-actin]-monooxygenase MICAL2, ERK2-binding testicular protein 1, MICAL C-terminal like, MICAL C-terminal-like protein, [F-actin]-methionine sulfoxide oxidase MICAL2, ebitein-1, flavoprotein oxidoreductase MICAL2, microtubule associated monoxygenase, calponin and LIM domain containing 2, molecule interacting with CasL protein 2, protein-methionine sulfoxide oxidase MICAL2

Rabbit

IgG

[F-actin]-monooxygenase MICAL2

Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin and regulates the SRF signaling. Acts by modifying nuclear actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization. Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA.

Human

-20°C or -80°C

41116161