MicroVue Complement Panel II - Focused (C1q, C3, C4, C5)

QuidelOrtho

MicroVue Complement Panel II - Focused (C1q, C3, C4, C5)

7

ELISA, Other Application

3 hours

Research Use Only

The MicroVue Complement Multiplex assays measures the amount of various complement proteins in human plasma or serum specimens. Choose between available off-the-shelf assays or have a custom kit developed with the specific analytes required (see Ordering Information below for more information). The included analytes are available in two panels: Panel 1: Ba, Bb, C2 Intact, C3a, C3d, C4a, C4d, C5a, sC5b-9, Factor D, Factor H, Factor I Panel 2: C1q, C2 Intact, C3 Intact, C4 Intact, C5 Intact, Factor D, Factor P Why two panels? Different complement proteins are found in different amounts withing serum/plasma. Panel 1 analytes require a 1:100 dilution while Panel 2 analytes require a 1:1000 dilution. For custom panels, only analytes within the same panel can be placed into the same multiplex assay. Compatibility Certain analytes cannot be combined into the same custom multiplex assays due to cross-reactivity. Incompatible analytes include: Panel 1: C3a and C3d Panel 1: C4a and C4d There are numerous immunological methods for complement testing, including individual protein ELISA-based kits measuring complement cleavage products as markers of complement activation. However, the ability to measure multiple complement proteins in an individual sample constitutes a major step forward in research-based tools. The MicroVue Complement Multiplex assays can measure the amount of many individual complement proteins and provide a comprehensive overview of complement system homeostasis and activation.

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