MICU1 Monoclonal Antibody
RD85534A
ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMICU1
Overview
- SupplierReddot Biotech
- Product NameMICU1 Monoclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDClone:4E7
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID10367
- Target nameMICU1
- Target descriptionmitochondrial calcium uptake 1
- Target synonymsara CALC; atopy-related autoantigen CALC; CALC; calcium uptake protein 1, mitochondrial; calcium-binding atopy-related autoantigen 1; CBARA1; EFHA3; MPXPS
- HostMouse
- IsotypeIgG
- Scientific DescriptionThis gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. MICU1 (Mitochondrial Calcium Uptake 1) is a Protein Coding gene. Diseases associated with MICU1 include Myopathy With Extrapyramidal Signs and Fish Allergy. Among its related pathways are Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is MICU3.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203