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ProductsBack/MICU2 Antibody

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA818265LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA818265LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA818265LA01HU at dilution of 1:100

MICU2 Antibody

CSB-PA818265LA01HU

ApplicationsELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetMICU2

Overview

Supplier
Cusabio
Product Name
MICU2 Antibody
Delivery Days Customer
20
Applications
ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID221154
Target name
MICU2
Target description
mitochondrial calcium uptake 2
Target synonyms
1110008L20Rik, EFHA1, hMICU3, calcium uptake protein 2, mitochondrial, EF hand domain family A1, EF hand domain family, member A1, EF-hand domain-containing family member A1, Smhs2 homolog
Host
Rabbit
Isotype
IgG
Protein IDQ8IYU8
Protein Name
Calcium uptake protein 2, mitochondrial
Scientific Description
Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low (PubMed:24503055, PubMed:24560927, PubMed:26903221). MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium (PubMed:24560927). MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering (PubMed:24560927).
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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