Midostaurin-d5

MedChem Express

Midostaurin-d5

9

Research Use Only

98.0

C35H25D5N4O4

575.67

Midostaurin-d 5 is a deuterium labeled Midostaurin. Midostaurin is a multi-targeted protein kinase inhibitor which inhibits PKCalpha/beta/gamma, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRbeta and VEGFR1/2 with IC50s ranging from 22-500 nM[1].

O=C(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])N(C)[C@H]2[C@@H](OC)[C@@]3(C)N(C4=C5C=CC=C4)C6=C5C7=C(C(NC7)=O)C8=C6N(C9=CC=CC=C98)[C@@](O3)([H])C2

-20°C,2°C to 8°C

12352200