Migalastat-d5

MedChem Express

Migalastat-d5

5

Research Use Only

C6H8D5NO4

168.20

Migalastat-d5 (GR181413A-d5 (free base)) is deuterium labeled Migalastat. Migalastat (GR181413A free base) is an orally active alpha-galactosidase A molecular chaperone, with an IC50 value of 0.04 microM for human alpha-Gal A. Migalastat binds to the active site of certain unstable mutant forms of alpha-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant alpha-galactosidase A to exhibit biological activity[1].

O[C@]1(CN[C@@H]([C@](O)([C@]1([2H])O)[2H])C(O)([2H])[2H])[2H]

12352200