Migalastat (hydrochloride)

MedChem Express

Migalastat (hydrochloride) [75172-81-5]

9

75172-81-5

Research Use Only

99.0

C6H14ClNO4

199.63

Migalastat (GR181413A free base) hydrochloride is an orally active alpha-galactosidase A molecular chaperone, with an IC 50 value of 0.04 microM for human alpha-Gal A. Migalastat binds to the active site of certain unstable mutant forms of alpha-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant alpha-galactosidase A to exhibit biological activity [1] .

O[C@H]1[C@@H](CO)NC[C@H](O)[C@H]1O.Cl

2°C to 8°C

12352200