Milademetan

MedChem Express

Milademetan [1398568-47-2]

5

1398568-47-2

98.87

C30H34Cl2FN5O4

618.53

Milademetan (DS-3032) is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) induces G1 cell cycle arrest , senescence and apoptosis [1] [2] .

O=C(NC1=CC(Cl)=CC=C21)[C@]32C4(CCC(C)(C)CC4)N[C@@H](C(N[C@@H]5CC[C@@H](C(N)=O)OC5)=O)[C@@H]3C6=CC=NC(Cl)=C6F

-20°C,2°C to 8°C

12352200