Milvexian

MedChem Express

Milvexian [1802425-99-5]

10

1802425-99-5

Research Use Only

99.93

C28H23Cl2F2N9O2

626.44

Milvexian is an orally bioavailable, small-molecule, reversible, direct antagonists of factor Xia , with the K i of 0.11, 0.38, 0.64, 490, 350 nM for human, rabbit, dog, rat, mouse, respectively. Milvexian shows anti-thrombosis activity in vitro and in vivo, and can be used for thrombus study [1] .

O=C(NC1=C2N(C(F)F)N=C1)[C@H](C)CCC[C@H](N(C=NC(C3=CC(Cl)=CC=C3N4N=NC(Cl)=C4)=C5)C5=O)C6=CC2=CC=N6

-20°C,2°C to 8°C

12352200