Western blot analysis of extracts from COLO cells, using MAP4K6 antibody.
Western blot analysis of extracts from COLO cells, using MAP4K6 antibody.
MINK1 Antibody
CSB-PA170472
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetMINK1
Overview
- SupplierCusabio
- Product NameMINK1 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID50488
- Target nameMINK1
- Target descriptionmisshapen like kinase 1
- Target synonymsB55; GCK family kinase MINK; MAP4K6; MAPK/ERK kinase kinase kinase 6; MEK kinase kinase 6; MEKKK 6; MINK; misshapen/NIK-related kinase; misshapen-like kinase 1; mitogen-activated protein kinase kinase kinase kinase 6; YSK2; ZC3
- HostRabbit
- IsotypeIgG
- Protein IDQ8N4C8
- Protein NameMisshapen-like kinase 1
- Scientific DescriptionSerine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1. Isoform 4 can activate the JNK pathway. Involved in the regulation of actin cytoskeleton reorganization, cell-matrix adhesion, cell-cell adhesion and cell migration. Dan I., FEBS Lett. 469:19-23(2000). Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Olsen J.V., Cell 127:635-648(2006).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203