
IHC image of CSB-PA865167LA01HU diluted at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
MIOS Antibody
CSB-PA865167LA01HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetMIOS
Overview
- SupplierCusabio
- Product NameMIOS Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID54468
- Target nameMIOS
- Target descriptionmeiosis regulator for oocyte development
- Target synonymsMIO, Sea4, Yulink, GATOR2 complex protein MIOS, GATOR complex protein MIOS, H_DJ1159O04.1, WD repeat-containing protein mio, WUGSC:H_DJ1159O04.1, missing oocyte, meiosis regulator, homolog
- HostRabbit
- IsotypeIgG
- Protein IDQ9NXC5
- Protein NameGATOR2 complex protein MIOS
- Scientific DescriptionAs a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161


