MIP-3 alpha/CCL20, Bovine (His-SUMO)

MedChem Express

MIP-3 alpha/CCL20, Bovine (His-SUMO)

10

Research Use Only

CCL20

C-C motif chemokine ligand 20

C-C motif chemokine 20, MIP-3-alpha, chemokine (C-C motif) ligand 20, macrophage inflammatory protein 3 alpha, small-inducible cytokine A20

C-C motif chemokine 20

The MIP-3 alpha/CCL20 protein acts as a ligand for CCR6, inducing an efficient chemotactic response and intracellular calcium mobilization upon CCR6 binding. The CCL20-CCR6 pair is critical in chemotaxis, attracting dendritic cells, effector/memory T cells, and B cells, especially to skin and mucosal surfaces during homeostasis, inflammation, cancer, and autoimmune diseases. MIP-3 alpha/CCL20 Protein, Bovine (His-SUMO) is the recombinant bovine-derived MIP-3 alpha/CCL20 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.

41116100