MIPS521

MedChem Express

MIPS521 [1146188-19-3]

10

1146188-19-3

Research Use Only

98.21

C19H10ClF6NOS

449.80

MIPS521 is a positive allosteric modulator of adenosine A1 receptor (A1AR). MIPS521 also has a lower A1R allosteric affinity (pKB=4.95; KB=11 microM). MIPS521 exhibits pain-relieving effects in vivo through modulation of the increased levels of endogenous adenosine[1][2].

O=C(C1=C(N)SC=C1C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C3=CC=C(C=C3)Cl

-20°C,2°C to 8°C

12352200