Miransertib

MedChem Express

Miransertib [1313881-70-7]

10

1313881-70-7

Research Use Only

99.32

C27H24N6

432.52

Miransertib (ARQ-092) is a potent, orally active, selective and allosteric Akt inhibitor with IC 50 s of 2.7 nM, 14 nM and 8.1 nM for Akt1 , Akt2 , Akt3 , respectively. Miransertib is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research [1] . Miransertib is effective against Leishmania [2] .

NC1=NC=CC=C1C2=NC3=CC=C(C4=CC=CC=C4)N=C3N2C5=CC=C(C6(N)CCC6)C=C5

-20°C,2°C to 8°C

12352200