Mist1 antibody [6E8/A12/C11P1]

GeneTex

Mist1 antibody [6E8/A12/C11P1]

9

WB: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

6E8/A12/C11P1

1 mg/ml

Unconjugated

BHLHA15

basic helix-loop-helix family member a15

BHLHB8, MIST1, class A basic helix-loop-helix protein 15, MIST-1, basic helix-loop-helix domain containing, class B, 8, class B basic helix-loop-helix protein 8, class II bHLH protein MIST1, muscle, intestine and stomach expression 1

Mouse

IgG

Class A basic helix-loop-helix protein 15

Mist 1 plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. This protein also negatively regulates bHLH-mediated transcription through an N-terminal repressor domain, and serves as a key regulator of acinar cell function, stability, and identity. Mist 1 is also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport, and may function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages.

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203