More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/MITF antibody [C5 + D5]

MITF antibody [C5 + D5]

Research Use Only
GTX01743
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetMITF
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    GeneTex
  • Product Name
    MITF antibody [C5 + D5]
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Clone ID
    C5 + D5
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID4286
  • Target name
    MITF
  • Target description
    melanocyte inducing transcription factor
  • Target synonyms
    bHLHe32; class E basic helix-loop-helix protein 32; CMM8; COMMAD; melanogenesis associated transcription factor; MI; microphtalmia-associated transcription factor; microphthalmia-associated transcription factor; MITF-A; WS2; WS2A
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDO75030
  • Protein Name
    Microphthalmia-associated transcription factor
  • Scientific Description
    The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Pulmonary melanocytic nevus - A case report with a mutation analysis of common driver oncogenes. Tanaka M et al., 2019 Nov, Pathol Int
    Read more
  • Is melanocyte density our last hope? Comparison of histologic features of photodamaged skin and melanoma in situ after staged surgical excision with concurrent scouting biopsies. Speiser J et al., 2019 Aug, J Cutan Pathol
    Read more
  • Immunohistochemical expression of melanocytic and myofibroblastic markers and their molecular correlation in atypical fibroxanthomas and pleomorphic dermal sarcomas. Helbig D et al., 2018 Dec, J Cutan Pathol
    Read more
  • New observations in tumor cell plasticity: mutational profiling in a case of metastatic melanoma with biphasic sarcomatoid transdifferentiation. Rupp NJ et al., 2018 Oct, Virchows Arch
    Read more
  • VMD2 promoter requires two proximal E-box sites for its activity in vivo and is regulated by the MITF-TFE family. Esumi N et al., 2007 Jan 19, J Biol Chem
    Read more
  • Elevated expression of MITF counteracts B-RAF-stimulated melanocyte and melanoma cell proliferation. Wellbrock C et al., 2005 Aug 29, J Cell Biol
    Read more