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Mitotane

HY-13690
MedChem Express
CAS Number53-19-0
DownloadMSDS
Product group Chemicals
Estimated Purity99.94
Molecular Weight320.04
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Mitotane [53-19-0]
  • Delivery Days Customer
    10
  • CAS Number
    53-19-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.94
  • Molecular Formula
    C14H10Cl4
  • Molecular Weight
    320.04
  • Scientific Description
    Mitotane (2,4-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions [1] [2] [3] [4] .
  • SMILES
    ClC1=CC=C(C(C2=CC=CC=C2Cl)C(Cl)Cl)C=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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