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Mitoxantrone-d8 (hydrochloride)

HY-13502AS1
MedChem Express
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Mitoxantrone-d8 (hydrochloride)
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Scientific Description
    Mitoxantrone-d8 (hydrochloride) (Mitozantrone-d8 (hydrochloride)) is deuterium labeled Mitoxantrone (dihydrochloride). Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 microM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity[1][2][3][4]. Mitoxantrone dihydrochloride also has anti-orthopoxvirus activity with EC50s of 0.25 microM and and 0.8 microM for cowpox and monkeypox, respectively[5].
  • UNSPSC
    12352200