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Mitoxantrone (diacetate)

Research Use Only
HY-13502B
MedChem Express
CAS Number70711-41-0
Product group Chemicals
Molecular Weight564.58
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Mitoxantrone (diacetate) [70711-41-0]
  • Delivery Days Customer
    10
  • CAS Number
    70711-41-0
  • Certification
    Research Use Only
  • Molecular Formula
    C26H36N4O10
  • Molecular Weight
    564.58
  • Scientific Description
    Mitoxantrone diacetate is a potent topoisomerase II inhibitor. Mitoxantrone diacetate also inhibits protein kinase C ( PKC ) activity with an IC 50 of 8.5 microM. Mitoxantrone diacetate induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone diacetate shows antitumor activity [1] [2] [3] [4] . Mitoxantrone diacetate also has anti- orthopoxvirus activity with EC 50 s of 0.25 microM and and 0.8 microM for cowpox and monkeypox, respectively [5] .
  • SMILES
    O=C1C2=C(C(NCCNCCO)=CC=C2NCCNCCO)C(C3=C(O)C=CC(O)=C13)=O.O=C(C)O.O=C(C)O
  • UNSPSC
    12352200