Mitoxantrone (Standard)

MedChem Express

Mitoxantrone (Standard) [65271-80-9]

5

Research Use Only

Mitoxantrone (Standard) is the analytical standard of Mitoxantrone. This product is intended for research and analytical applications. Mitoxantrone is a potent topoisomerase II inhibitor. Mitoxantrone also inhibits protein kinase C ( PKC ) activity with an IC 50 of 8.5 microM. Mitoxantrone induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone shows antitumor activity [1] [2] [3] [4] . Mitoxantrone also has anti- orthopoxvirus activity with EC 50 s of 0.25 microM and and 0.8 microM for cowpox and monkeypox, respectively [5] .

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