MK-0752 [471905-41-6]
HY-10974
CAS Number471905-41-6
Product group Chemicals
Estimated Purity99.35
Molecular Weight442.90
Overview
- SupplierMedChem Express
- Product NameMK-0752 [471905-41-6]
- Delivery Days Customer10
- CAS Number471905-41-6
- Category SupplierCHEMICAL,general_chemicals_reagents
- CertificationResearch Use Only
- Estimated Purity99.35
- Molecular FormulaC21H21ClF2O4S
- Molecular Weight442.90
- Scientific DescriptionMK-0752 is a potent, orally active and specific gamma-secretase inhibitor, showing dose-dependent reduction of Abeta40 with an IC50 of 5 nM in human SH-SY5Y cells. MK-0752 crosses the blood-brain barrier. MK-0752 reduces newly generated CNS Abeta in vivo[1][2].
- SMILESO=S([C@@]1(C2=C(C=CC(F)=C2)F)CC[C@@H](CCC(O)=O)CC1)(C3=CC=C(Cl)C=C3)=O
- Storage Instruction-20°C, 3 years; 4°C, 2 years (Powder)
- UNSPSC12352200
![MK-0752 [471905-41-6]](https://www.targetmol.com/group3/M00/02/C1/CgoaEGY7PQ-EJj4eAAAAAE_vFBo599.png)