MK-0752 (sodium) [656810-87-6]
HY-10975
CAS Number656810-87-6
Product group Chemicals
Molecular Weight464.89
Overview
- SupplierMedChem Express
- Product NameMK-0752 (sodium) [656810-87-6]
- Delivery Days Customer9
- CAS Number656810-87-6
- CertificationResearch Use Only
- Molecular FormulaC21H20ClF2NaO4S
- Molecular Weight464.89
- Scientific DescriptionMK-0752 sodium is a potent, orally active and specific gamma-secretase inhibitor, showing dose-dependent reduction of Abeta40 with an IC50 of 5 nM in human SH-SY5Y cells. MK-0752 sodium crosses the blood-brain barrier. MK-0752 sodium reduces newly generated CNS Abeta in vivo[1][2].
- SMILESO=C(CC[C@H]1CC[C@@](C2=CC(F)=CC=C2F)(S(=O)(C3=CC=C(Cl)C=C3)=O)CC1)O[Na]
- UNSPSC12352200