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MK-2206 dihydrochloride

Research Use Only
T1952
TargetMol Chemicals
CAS Number1032350-13-2
Product group Chemicals
Molecular Weight480.39
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    MK-2206 dihydrochloride
  • Delivery Days Customer
    4
  • CAS Number
    1032350-13-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    MK-2206 dihydrochloride
  • Molecular Formula
    C25H23Cl2N5O
  • Molecular Weight
    480.39
  • Scientific Description
    MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and selective potency. MK-2206 dihydrochloride exhibits antitumor activity.
  • Shelf life instruction
    3 years
  • SMILES
    Cl.Cl.NC1(CCC1)c1ccc(cc1)-c1nc2ccn3c(n[nH]c3=O)c2cc1-c1ccccc1
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Hirai H, et al. MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo. Mol Cancer Ther. 2010 Jul;9(7):1956-67.
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