MK-2206 (free base) [1032349-93-1]
HY-10357
CAS Number1032349-93-1
Product group Chemicals
Molecular Weight407.47
Overview
- SupplierMedChem Express
- Product NameMK-2206 (free base) [1032349-93-1]
- Delivery Days Customer14
- CAS Number1032349-93-1
- CertificationResearch Use Only
- Molecular FormulaC25H21N5O
- Molecular Weight407.47
- Scientific DescriptionMK-2206 free base is an orally active, highly potent and selective allosteric Akt inhibitor, with IC50s of 8, 12, and 65 nM for Akt1, Akt2, and Akt3, respectively. Many breast cancer cell lines, and PIK3CA-mutant and cell lines with PTEN loss are sensitive to MK-2206 free base. MK-2206 free base has anticancer activities[1][2].
- SMILESO=C1N2C(C3=CC(C4=CC=CC=C4)=C(C(C=C5)=CC=C5C6(CCC6)N)N=C3C=C2)=NN1
- UNSPSC12352200