MK-2206 free base [1032349-93-1]

TargetMol Chemicals

MK-2206 free base [1032349-93-1]

16

Chemical

Research Use Only

MK-2206 free base

C25H21N5O

407.47

MK-2206 free base is a potent, selective, and orally administered allosteric Akt inhibitor with IC50 values of 8, 12, and 65 nM for Akt1, Akt2, and Akt3, respectively. It demonstrates sensitivity in various breast cancer cell lines, including those with PIK3CA mutations and PTEN loss, indicating its potential for anticancer activities [1] [2].

3 years

O=C1NN=C2C=3C=C(C=4C=CC=CC4)C(=NC3C=CN12)C=5C=CC(=CC5)C6(N)CCC6

-20°C

12352200