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MK-2461

M3515
AbMole BioScience
CAS Number917879-39-1
DownloadDatasheet
Product group Chemicals
Estimated Purity>99.0%
Molecular Weight495.55
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    MK-2461
  • Delivery Days Customer
    9
  • CAS Number
    917879-39-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    >99.0%
  • Molecular Formula
    C24H25N5O5S
  • Molecular Weight
    495.55
  • Scientific Description
    MK-2461 is a potent, multi-targeted inhibitor for c-Met(WT/mutants) with IC50 of 0.4-2.5 nM, less potent to Ron, Flt1; 8- to 30-fold greater selectivity of c-Met targets versus FGFR1, FGFR2, FGFR3, PDGFRbèta, KDR, Flt3, Flt4, TrkA, and TrkB.
  • SMILES
    CN(CC1COCCO1)[S](=O)(=O)NC2=CC3=C(C=C2)C=CC4=C(C=C(C=N4)C5=C[N](C)N=C5)C3=O
  • UNSPSC
    12352200

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