MK-2894

MedChem Express

MK-2894 [1006036-87-8]

10

1006036-87-8

Research Use Only

99.31

C25H22F3NO3S

473.51

MK-2894 is a potent, selective, orally active and high affinity ( K i =0.56 nM) full antagonist against E prostanoid receptor 4 (EP4 receptor) ( IC 50 =2.5 nM). MK-2894 possesses potent anti-inflammatory activity in animal models of pain/inflammation and can be used for the research of arthritis [1] [2] .

O=C(O)C1=CC=C(C2(NC(C3=C(C)SC(C)=C3CC4=CC=C(C(F)(F)F)C=C4)=O)CC2)C=C1

-20°C,2°C to 8°C

12352200