MK-8745

AbMole BioScience

MK-8745

9

885325-71-3

Research Use Only

C20H19ClFN5OS

431.91

MK-8745 is a potent and selective Aurora A inhibitor with IC50 of 0.6 nM, more than 450-fold selectivity for Aurora A over Aurora B.

FC1=C(C=CC=C1Cl)C(=O)N2CCN(CC2)CC3=CC=CC(=N3)NC4=NC=CS4

12352200