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MK-886

HY-14166
MedChem Express
CAS Number118414-82-7
Product group Chemicals
Estimated Purity99.77
Molecular Weight472.08
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MK-886 [118414-82-7]
  • Delivery Days Customer
    10
  • CAS Number
    118414-82-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.77
  • Molecular Formula
    C27H34ClNO2S
  • Molecular Weight
    472.08
  • Scientific Description
    MK-886 (L 663536) is a potent, cell-permeable and orally active FLAP ( IC 50 of 30 nM) and leukotriene biosynthesis ( IC 50 s of 3 nM and 1.1 microM in intact leukocytes and human whole blood, respectively) inhibitor. MK-886 is also a non-competitive PPARalpha antagonist and can induce apoptosis [1] [2] [3] .
  • SMILES
    CC(C)C1=CC=C(N(CC2=CC=C(Cl)C=C2)C(CC(C)(C(O)=O)C)=C3SC(C)(C)C)C3=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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