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MK2-IN-3 (hydrate)

HY-112457
MedChem Express
CAS Number1186648-22-5
Product group Chemicals
Estimated Purity99.0
Molecular Weight358.39
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MK2-IN-3 (hydrate) [1186648-22-5]
  • Delivery Days Customer
    10
  • CAS Number
    1186648-22-5
  • Certification
    Research Use Only
  • Estimated Purity
    99.0
  • Molecular Formula
    C21H18N4O2
  • Molecular Weight
    358.39
  • Scientific Description
    MK2-IN-3 hydrate (compound 16) is an orally active, selective, and ATP-competitive MAPKAP-K2 (MK-2) inhibitor with an IC 50 of 0.85 nM.MK2-IN-3 hydrate is exceptional selectivity against MK-3 ( IC 50 =0.21 microM), MK-5 ( IC 50 =0.081 microM), ERK2 ( IC 50 =3.44 microM), MNK1( IC 50 =5.7 microM) as well as CDK2, JNK2, IKK2, MSK1, and MSK2 [1] .
  • SMILES
    O=C1C2=C(NC(C3=CC(C4=CC5=CC=CC=C5N=C4)=NC=C3)=C2)CCN1.O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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