MKC-1 [125313-92-0]

MedChem Express

MKC-1 [125313-92-0]

10

125313-92-0

Research Use Only

99.78

C22H16N4O4

400.39

MKC-1 (Ro-31-7453) is an orally active and potent cell cycle inhibitor with broad antitumor activity. MKC-1 inhibits the Akt/mTOR pathway. MKC-1 arrests cellular mitosis and induces cell apoptosis by binding to a number of different cellular proteins including tubulin and members of the importin beta family[1][2][3].

O=C(C(C1=CN(C)C2=C1C=CC=C2)=C3C4=CN(C)C5=C4C=CC([N+]([O-])=O)=C5)NC3=O

-20°C,2°C to 8°C

12352200