ML 145

MedChem Express

ML 145 [1164500-72-4]

10

1164500-72-4

Research Use Only

97.04

C24H22N2O5S2

482.57

ML 145 is a selective and competitive human GPR35/CXCR8 antagonist with an IC 50 / EC 50 of 20.1 nM. ML 145 has over 1000-fold more selective for GPR35 compared to GPR55 (IC 50 /EC 50 =21.7 microM) [1] . ML 145 has no significant activity for GPR35 at either rodent ortholog [2] .

CC(/C=C(S1)/C(N(CCCC(NC2=CC(O)=C(C(O)=O)C=C2)=O)C1=S)=O)=C\C3=CC=CC=C3

-20°C,2°C to 8°C

12352200