ML-180 [863588-32-3]

MedChem Express

ML-180 [863588-32-3]

9

863588-32-3

Research Use Only

99.96

C20H25ClN4O2

388.89

ML-180 (SR1848) is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist with an IC50 of 3.7 microM. ML-180 is inactive for steroidogenic factor-1 (SF-1; NR5A1; IC50>10 microM). ML-180 has the potential for LRH-1-dependent cancers[1][2].

O=C1N(C2CCCCC2)C(C=C(N3CCN(C4=CC=CC(Cl)=C4)CC3)N1)=O

2°C to 8°C

12352200