ML 210
M8380
CAS Number1360705-96-9
Product group Chemicals
Molecular Weight475.32
Overview
- SupplierAbMole BioScience
- Product NameML 210
- Delivery Days Customer9
- CAS Number1360705-96-9
- Category SupplierChemical
- CertificationResearch Use Only
- Molecular FormulaC22H20Cl2N4O4
- Molecular Weight475.32
- Scientific DescriptionMl-210 is a selective, covalent glutathione peroxidase 4 (GPX4) inhibitor with an EC50 of 30 nM. Ml-210 binds GPX4 selenocysteine residues. ML210 has anticancer activity and has shown cytotoxic effects on melanoma, lung adenocarcinoma, fibrosarcoma and pancreatic cancer cell lines.
- SMILESCC1=C(C(=NO1)C(=O)N2CCN(CC2)C(C3=CC=C(Cl)C=C3)C4=CC=C(Cl)C=C4)[N+]([O-])=O
- UNSPSC12352200