ML-323 [1572414-83-5]
T1757
CAS Number1572414-83-5
Product group Chemicals
Estimated Purity99.96%
Molecular Weight384.48
Overview
- SupplierTargetMol Chemicals
- Product NameML-323 [1572414-83-5]
- Delivery Days Customer9
- CAS Number1572414-83-5
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameML-323
- Estimated Purity99.96%
- Molecular FormulaC23H24N6
- Molecular Weight384.48
- Scientific DescriptionML323 is a reversible and effective USP1-UAF1 inhibitor in a Ub-Rho assay (IC50: 76 nM) and in orthogonal gel-based assays using K63-linked diubiquitin (di-Ub) (IC50: 174 nM 820 nM)and monoubiquitinated PCNA (Ub-PCNA) (IC50: 820 nM) as substrates, respectively.
- Shelf life instruction3 years
- SMILESCC(C)c1ccccc1-c1ncc(C)c(NCc2ccc(cc2)-n2ccnn2)n1
- Storage Instruction-20°C
- UNSPSC12352200
References
- A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses. Liang Q et al., 2014 Apr, Nat Chem BiolRead more