ML-7 [109376-83-2]

MedChem Express

ML-7 [109376-83-2]

9

109376-83-2

Research Use Only

C15H17IN2O2S

416.28

ML-7 is a myosin light chain kinase inhibitor with the activity to inhibit superoxide anion (O(2)(-)) release in human neutrophils. ML-7 can affect the activity of neutrophils independently of myosin light chain kinase. ML-7 inhibits the extracellular O(2)(-) release of stimulated cells, but has no effect on the intracellular O(2)(-) production. ML-7 also strongly inhibits the binding of the intracellular compartment of oxide production to the cell membrane, indicating that it plays a key role in stimulated neutrophils. At the same time, ML-7 protects cardiac function from ischemia/reperfusion injury[1].

O=S(N1CCNCCC1)(C2=C3C=CC=C(C3=CC=C2)I)=O

12352200