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ML115 [912798-42-6]

HY-111152
MedChem Express
CAS Number912798-42-6
Product group Chemicals
Estimated Purity99.89
Molecular Weight322.74
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ML115 [912798-42-6]
  • Delivery Days Customer
    5
  • CAS Number
    912798-42-6
  • Certification
    Research Use Only
  • Estimated Purity
    99.89
  • Molecular Formula
    C15H15ClN2O4
  • Molecular Weight
    322.74
  • Scientific Description
    ML115, a molecular probe of the signal transducer, is a selective STAT3 agonist, with an EC50 of 2 nM. ML115 increases the expression of BCL3, a known STAT3-dependent oncogene. ML115 is inactive against the related STAT1, STAT5 and NF-kappaB anti-targets. ML115 counteracts the effects of Ginsenoside Rc (HY-N0042) on cell viability and inflammatory responses in LPS (HY-D1056)-stimulated H9c2 and RAW264.7 cells, while altering oxidative stress markers. ML115 can be used for the study of breast and prostate cancers[1][2].
  • SMILES
    O=C(C1=NOC(C2CC2)=C1)NC3=CC(OC)=C(Cl)C=C3OC
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200