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ML154

HY-108626
MedChem Express
CAS Number1345964-89-7
Product group Chemicals
Estimated Purity99.59
Molecular Weight545.47
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ML154 [1345964-89-7]
  • Delivery Days Customer
    5
  • CAS Number
    1345964-89-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.59
  • Molecular Formula
    C29H26BrN2PS
  • Molecular Weight
    545.47
  • Scientific Description
    ML154 (NCGC84) is a selective, brain-penetrant and non-peptide neuropeptide S receptor (NPSR) antagonist with a pA 2 of 9.98. ML154 potently inhibits NPS-stimulated cellular calcium, cAMP, and ERK phosphorylation responses with IC 50 values of 36.5 nM, 22.1 nM, and 9.3 nM, respectively [1] [2] .
  • SMILES
    S=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=C(C)[N+](C/C=C/C4=CC=CC=C4)=C5N3C=CC=C5.[Br-]
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200