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ML216

HY-12342
MedChem Express
CAS Number1430213-30-1
DownloadMSDS
Product group Chemicals
Estimated Purity99.89
Molecular Weight383.32
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ML216 [1430213-30-1]
  • Delivery Days Customer
    10
  • CAS Number
    1430213-30-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.89
  • Molecular Formula
    C15H9F4N5OS
  • Molecular Weight
    383.32
  • Scientific Description
    ML216 (CID-49852229) is a potent, selective and cell permeable inhibitor of the DNA unwinding activity of BLM helicase with IC 50 s of 2.98 microM and 0.97 microM for BLM full-length and BLM 636-1298 , respectively. ML216 inhibits ssDNA-dependent ATPase activity of BLM with a K i of 1.76 microM. Antitumor avtivity [1] [2] .
  • SMILES
    O=C(NC1=CC=C(F)C(C(F)(F)F)=C1)NC2=NN=C(S2)C3=CC=NC=C3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200