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ProductsBack/ML221 [877636-42-5]

ML221 [877636-42-5]

Research Use Only
HY-103254
MedChem Express
CAS Number877636-42-5
DownloadMSDS
Product group Chemicals
Estimated Purity99.55
Molecular Weight385.35
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ML221 [877636-42-5]
  • Delivery Days Customer
    10
  • CAS Number
    877636-42-5
  • Certification
    Research Use Only
  • Estimated Purity
    99.55
  • Molecular Formula
    C17H11N3O6S
  • Molecular Weight
    385.35
  • Scientific Description
    ML221 is a potent apelin (APJ) functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 microM in the cAMP assay, and 1.75 microM in the beta-arrestin assay, and EC80 of 10 nM in both assays.
  • SMILES
    O=C1C=C(CSC2=NC=CC=N2)OC=C1OC(C3=CC=C([N+]([O-])=O)C=C3)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200