ML334

MedChem Express

ML334 [1432500-66-7]

10

1432500-66-7

Research Use Only

99.76

C26H26N2O5

446.50

ML334 is a potent, cell permeable activator of NRF2 by inhibition of Keap1-NRF2 protein-protein interaction. ML334 binds to Keap1 Kelch domain with a K d of 1 microM. ML334 stimulates NRF2 expression and nuclear translocation and induces antioxidant response elements (ARE) activity [1] [2] .

O=C(C1=CC=CC=C1C2=O)N2C[C@@H]3C4=CC=CC=C4CCN3C([C@H]5[C@H](CCCC5)C(O)=O)=O

2°C to 8°C

12352200